Tag: Genetic component

Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior

範疇(D) 同性戀研究 1.ii 科學研究.原因
編號D1ii0011
作者Andrea Ganna, Karin J. H. Verweij, Michel G. Nivard, Robert Maier, Robbee Wedow, Alexander S. Busch, Abdel Abdellaoui, Shengru Guo, J. Fah Sathirapongsasuti, 23andMe Research Team, Paul Lichtenstein, Sebastian Lundström, Niklas Långström, Adam Auton, Kathleen Mullan Harris, Gary W. Beecham, Eden R. Martin, Alan R. Sanders, John R. B. Perry, Benjamin M. Neale, Brendan P. Zietsch
題目Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior
日期20190830
簡介Twin studies and other analyses of inheritance of sexual orientation in humans has indicated that same-sex sexual behavior has a genetic component. Previous searches for the specific genes involved have been underpowered and thus unable to detect genetic signals. Ganna et al. perform a genome-wide association study on 493,001 participants from the United States, the United Kingdom, and Sweden to study genes associated with sexual orientation. They find multiple loci implicated in same-sex sexual behavior indicating that, like other behavioral traits, nonheterosexual behavior is polygenic.
關鍵詞Sexual orientation, Genetic component, Same-sex sexual behavior, Polygenic, Twin studies
來源Science
連結https://www.science.org/doi/10.1126/science.aat7693